Ivermectin

Ivermectin

Classification – Parasite Infection Medicine

Ivermectin?

It is a medicine used to kill parasites or worms and is widely used in parasitic infections. It is WHO's recommended essential medicine.

Uses of Ivermectin

Used against parasitic infections:

• • Filarial worms
• • River blindness
• • Scabies
• • Head lice
• • Hook-worm infection

Working of Ivermectin

• • It causes paralysis of the parasite
• • Kills parasites

Benefits

• • It has a broad spectrum of activity, used against many parasites
• • Useful in community treatment initiatives
• • Well tolerated
• • Repeated doses are safe

Common Side Effects

• • Headache
• • Dizziness
• • Muscle pain
• • Diarrhea
• • Skin rashes
• • Fever

Serious Side Effects

• • Peeling of the skin
• • Severely low blood pressure
• • Seizures
• • Mental confusion
• • Inflammation in the brain

Precautions

To be cautiously used in –

• • Psychiatric disorders – seizures, depression
• • Severe liver disorder
• • Pregnant and breastfeeding women
• • High parasitic burden
• • Elderly patients
• • With CNS depressant drugs

Contraindications

• • Allergy to Ivermectin
• • Meningitis
• • 1st trimester of pregnancy
• • Severe liver impairment
• • Children weighing less than 15kg or under 5 years of age
• • Concomitant infections

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