Brand: Aprazer HealthcarePemeaxis 500mg Injection
Molecular Salt: Pemetrexed
PEMEAXIS 500mg InjectionComposition: Pemetrexed 500 mgCategory: Anticancer Medication
OverviewPemeaxis is a chemotherapy drug primarily prescribed for the treatment of certain types of lung cancer.
Therapeutic Uses
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• Non-small cell lung cancer (NSCLC)
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• Malignant pleural mesothelioma
Mechanism of ActionPemeaxis works by blocking folate metabolism within cancer cells, which disrupts DNA and RNA synthesis, thereby slowing or stopping cancer cell growth.
PrecautionsUse with caution in patients who have:
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• Liver disease
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• Kidney disease
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• Blood-related disorders
Drug InteractionsAvoid combining with:
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• NSAIDs and other kidney-toxic drugs
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• Live vaccines
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• Anticancer Medications that interfere with folate metabolism
Possible Side Effects
Common:
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• Fatigue and weakness
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• Nausea and vomiting
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• Bone marrow suppression
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• Mouth sores
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• Reduced appetite
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• Diarrhea
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• Fluid retention
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• Hair thinning or loss
Serious:
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• Severe myelosuppression
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• Allergic (anaphylactic) reactions
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• Liver toxicity
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• Kidney damage
ContraindicationsDo not use in:
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• Individuals allergic to its components
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• Pregnant or breastfeeding women
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• Patients with significant kidney impairment
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• People with severely low blood counts
Warnings & Recommendations
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• Use strictly under a doctor’s supervision.
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• Supplement with folic acid and vitamin B12 during treatment.
Monitoring During TherapyRegularly check:
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• Complete blood count
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• Liver function tests
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• Kidney function tests
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• Hydration status
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• Electrolyte levels
Storage Instructions
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• Keep refrigerated at 2–8 °C
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• Protect from direct light
Administration Guidelines
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• Administer only as a slow intravenous infusion
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• Use immediately after reconstitution
Aprazer Healthcare
Injection (500 mg)
Single Pack Unit
Store below 30°C
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Storage Warning: Biological injectables, biosimilars, and active oncology agents are flagged as temperature-sensitive cargo and are packed strictly inside thermal containers coupled with real-time digital temperature tags.