Paclikast 260 mg

Paclikast -260 mg

Composition:  Paclitaxel -260 mg

Classification: Anticancer Medicine

What is Paclitaxel?

It is a chemotherapy anti-cancer medicine, used against various cancers and solid tumors.

Uses of Paclikast

• Breast cancer

• Ovarian cancer

• AIDS related sarcoma

• Non-small cell lung cancer

• Pancreatic cancer

• Head and neck cancer

How Does It Work?

It inhibits the double-stranded DNA breakage to single-strand, inhibits the replication and multiplication of DNA.

Common Side Effects

• Tiredness

• Hair loss

• Increases the risk of infections

• Indigestion – diarrhea, constipation

• Hypotension

• Mouth ulcers

• Muscle and joint pain

• UTI

• Anemia

• Numbness of limbs, tingling in hands, fingers

Serious Side Effects

• Bone Marrow Suppression

• Slow heartbeat

• Shortness of breath

• Blood clot

• Chest pain

• Liver toxicity

• Local tissue injury

• Pain in the abdomen

Precautions

To be used cautiously in patients with –

• Liver disorders

• Renal disorders

• Hypertension patients

• Elderly patients

• Pre-existing infections

• Immune-compromised patients

• Adjuvant to myelosuppressive treatments

Contraindications

• Not to be used if any previous allergy or hypersensitivity to Paclitaxel or any excipients.

• Breastfeeding mothers

• Pregnant women

Warnings

To be used under the supervision of a medical practitioner or oncology specialist, having adequate diagnostic and monitoring facilities.

Important safety and monitoring information

Regularly monitor blood count, hepatic, manage infection risks, cardiac functions, and early signs of peripheral neuropathy.

Storage

It should be stored at 2-8 degrees Celsius, protected from light.

Administration Instructions

• To be administered as a slow IV infusion only.

• Do not give as an IV push/bolus.

• To be used immediately after reconstitution.